One True Thing

Meryl Streep

Kate Gulden

Renée Zellweger

Ellen Gulden

William Hurt

George Gulden

Tom Everett Scott

Brian Gulden

Lauren Graham

Jules

Nicky Katt

Jordan Belzer

James Eckhouse

District Attorney

Patrick Breen

G.A. Tweedy

Gerrit Graham

Oliver Most

David Byron

Senator Sullivan

Stephen Peabody

Harold

Lizbeth Mackay

Dr. Cohen

Mary Catherine Wright

Clarice

Sloane Shelton

Evelyn Best

Michele Shay

June

Bobo Lewis

Muriel

Marylouise Burke

Louisa

Marcia Jean Kurtz

Marcia

Diana Canova

Diana

John Deyle

Santa / Mayor

Hallee Hirsh

Ellen - Age 8

Jeffrey Scaperrotta

Brian - Age 4

Todd Cerveris

Casey

Anna Carolina Alvim

Nurse Teresa

Julie Janney

Hospital Nurse

Susan Stout

Tweedy's Secretary

Greg Hedtke

Magazine Executive

Christian James

Magazine Executive

Lauren Toub

Halloween Girl

Ashley Remy

Halloween Girl

Saul Williams

Graduate Student

Julianne Nicholson

College Student

Amber Kain

College Student

Yolande Bavan

Nari

Benjamin Andrews

Party Kid

Kathryn Walsh

Party Kid

Carl Franklin

Director

Anna Quindlen

Novel

Karen Croner

Screenplay

Jesse Beaton

Producer

Leslie Morgan

Executive Producer

Harry J. Ufland

Producer

William W. Wilson III

Executive Producer

Richard Pagano

Casting

Declan Quinn

Director of Photography

Paul Peters

Production Design

Jefferson Sage

Art Direction

Donna Zakowska

Costume Design